MECHENG 5180
Transcript Abbreviation:
Mech Biomolec Sys
Course Description:
Introduction to biomolecules and systems in the context of cellular functions. In particular the course focuses on the physical properties of biomolecules and the physical interactions that mediate their functions.
Course Levels:
Undergraduate (1000-5000 level)
Graduate (5000-8000 level)
Designation:
Elective
General Education Course:
(N/A)
Cross-Listings:
(N/A)
Credit Hours (Minimum if “Range”selected):
3.00
Max Credit Hours:
(N/A)
Select if Repeatable:
Off
Maximum Repeatable Credits:
(N/A)
Total Completions Allowed:
(N/A)
Allow Multiple Enrollments in Term:
No
Course Length:
14 weeks (autumn or spring)
12 weeks (summer only)
Off Campus:
Never
Campus Location:
Columbus
Instruction Modes:
In Person (75-100% campus; 0-24% online)
Prerequisites and Co-requisites:
Prereq: Sr or Grad standing in Engineering, or permission of instructor.
Electronically Enforced:
No
Exclusions:
Not open to students with credit for 694E (Spring 2010).
Course Goals / Objectives:
Introduces students to biological systems at the cellular and molecular scale and the importance of physical properties and interactions at that length scale
Gain understanding of how to utilize mechanical engineering concepts to describe biological systems
Learn about the physical structure of biological cells and learn about cellular processes such as migration and division
Learn how to combine traditional mechanics (i.e. beam mechanics) with statistical approaches to develop mechanical models for biological systems
Check if concurrence sought:
No
Contact Hours:
| Topic | LEC | REC out-of-class | REC in-class | Weekly LAB out-of-class | Weekly LAB in-class |
|---|---|---|---|---|---|
| Basics of structure of biological cells and molecules | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Diffusion of small molecules with and without applied forces | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Receptor-ligand binding kinetics | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Protein unfolding and refolding under force | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Rate-dependence of unfolding | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Function, structure, and stepping mechanisms of molecular motors | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Force generation and velocities of Molecular Motors | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Polymerization dynamics of biological filaments | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Thermal fluctuations of biopolymers | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Force-extension behavior of single polymers | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Microstructural modeling of biological networks and tissues | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Force Spectroscopy methods in biophysics | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Basic principles and methods for fluorescence microscopy | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Biomolecular Nanotechnology | 0.0 | 0.0 | 0 | 0.0 | 0 |
| Total | 0 | 0 | 0 | 0 | 0 |
Grading Plan:
Letter Grade
Course Components:
Lecture
Grade Roster Component:
Lecture
Credit by Exam (EM):
No
Grades Breakdown:
| Aspect | Percent |
|---|---|
| 2 Class Examinations | 50% |
| Homework (7 sets) | 25% |
| Term Project | 25% |
Representative Textbooks and Other Course Materials:
| Title | Author | Year |
|---|---|---|
| Course Notes for Molecular Biomechanics | Carlos Castro | |
| Physical Biology of the Cell | Phillips, Kondev, Theriot |
ABET-CAC Criterion 3 Outcomes:
(N/A)
ABET-ETAC Criterion 3 Outcomes:
(N/A)
ABET-EAC Criterion 3 Outcomes:
| Significant contribution (7+ hours) | 1 | an ability to identify, formulate, and solve complex engineering problems by applying principles of engineering, science, and mathematics |
| Substantial contribution (3-6 hours) | 3 | an ability to communicate effectively with a range of audiences - pre-2019 EAC SLO (g) |
| Some contribution (1-2 hours) | 4 | an ability to recognize ethical and professional responsibilities in engineering situations and make informed judgments, which must consider the impact of engineering solutions in global, economic, environmental, and societal contexts |
| Some contribution (1-2 hours) | 7 | an ability to acquire and apply new knowledge as needed, using appropriate learning strategies |
Embedded Literacies Info: