MATSCEN 3611
Transcript Abbreviation:
Bio Resp Biomat
Course Description:
The biological response to biomaterials implanted within the human body.
Course Levels:
Undergraduate (1000-5000 level)
Designation:
Required
Elective
General Education Course:
(N/A)
Cross-Listings:
(N/A)
Credit Hours (Minimum if “Range”selected):
3.00
Max Credit Hours:
(N/A)
Select if Repeatable:
Off
Maximum Repeatable Credits:
(N/A)
Total Completions Allowed:
(N/A)
Allow Multiple Enrollments in Term:
No
Course Length:
14 weeks (autumn or spring)
12 weeks (summer only)
Off Campus:
Never
Campus Location:
Columbus
Instruction Modes:
In Person (75-100% campus; 0-24% online)
Prerequisites and Co-requisites:
Prereq: 2010, or permission of instructor.
Electronically Enforced:
No
Exclusions:
(N/A)
Course Goals / Objectives:
Learn the concepts of biology that govern how the body reacts to the presence of modern biomaterials.
Learn concepts relating to how implants are labeled as `foreign? and the aggressive chemical response that often damages both the implant and surrounding natural tissues.
Study materials engineering strategies used to minimize or ignore these biological reactions.
Check if concurrence sought:
No
Contact Hours:
| Topic | LEC | REC out-of-class | REC in-class | Weekly LAB out-of-class | Weekly LAB in-class |
|---|---|---|---|---|---|
| The Immune System Self and non-self discrimination; Innate and adaptive immune response; molecular basis of T cell, B cell and antibody responses; inflammatory response, inflammatory mediators; surfaces and protein adsorption | 9.0 | 0.0 | 0 | 0.0 | 0 |
| Foreign body response Resorption, Integration, Encapsulation | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Metals Materials selection, effects of mechanical properties, chemistry and corrosion | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Ceramics Materials selection, effects of chemistry and processing | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Polymers: Natural and Synthetic Materials selection, effects of chemistry, molecular weight, degradation rate, wetting angle | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Surface Engineering Surface morphology, surface chemistry, surface energy | 3.0 | 0.0 | 0 | 0.0 | 0 |
| Tissue Engineered Biomaterials Cell sourcing, tissue typing, use of xenogenic and other naturally derived materials | 3.0 | 0.0 | 0 | 0.0 | 0 |
| Modifying the foreign body response: Case studies Orthopaedic Implants, surgical staples/sutures, dental implants, biosensors, cosmetic implants, tissue engineered skin | 9.0 | 0.0 | 0 | 0.0 | 0 |
| Total | 44 | 0 | 0 | 0 | 0 |
Grading Plan:
Letter Grade
Course Components:
Lecture
Grade Roster Component:
Lecture
Credit by Exam (EM):
No
Grades Breakdown:
| Aspect | Percent |
|---|---|
| Midterm 1 | 25% |
| Midterm 2 | 25% |
| Mini-case study in groups | 20% |
| Final | 30% |
Representative Textbooks and Other Course Materials:
| Title | Author | Year |
|---|---|---|
| Biological Performance of Materials: Fundamentals of Biocompatibility 3rd Edition | Jonathan Black |
ABET-CAC Criterion 3 Outcomes:
(N/A)
ABET-ETAC Criterion 3 Outcomes:
(N/A)
ABET-EAC Criterion 3 Outcomes:
| Substantial contribution (3-6 hours) | 1 | an ability to identify, formulate, and solve complex engineering problems by applying principles of engineering, science, and mathematics |
| Substantial contribution (3-6 hours) | 2 | an ability to apply engineering design to produce solutions that meet specified needs with consideration of public health, safety, and welfare, as well as global, cultural, social, environmental, and economic factors |
| Some contribution (1-2 hours) | 3 | an ability to communicate effectively with a range of audiences - pre-2019 EAC SLO (g) |
| Some contribution (1-2 hours) | 4 | an ability to recognize ethical and professional responsibilities in engineering situations and make informed judgments, which must consider the impact of engineering solutions in global, economic, environmental, and societal contexts |
| Some contribution (1-2 hours) | 5 | an ability to function effectively on a team whose members together provide leadership, create a collaborative and inclusive environment, establish goals, plan tasks, and meet objectives |
| Some contribution (1-2 hours) | 6 | an ability to develop and conduct appropriate experimentation, analyze and interpret data, and use engineering judgment to draw conclusions |
| Some contribution (1-2 hours) | 7 | an ability to acquire and apply new knowledge as needed, using appropriate learning strategies |
Embedded Literacies Info: