BIOMEDE 6530
Transcript Abbreviation:
E Cell Plasticity
Course Description:
Exploration of underlying mechanisms of inherent and/or induced cell and tissue plasticity within the context of disease and therapy, as well as a number of engineering approaches (e.g., cellular, molecular) towards modulating cellular plasticity for therapy.
Course Levels:
Graduate (5000-8000 level)
Designation:
Required
General Education Course:
(N/A)
Cross-Listings:
(N/A)
Credit Hours (Minimum if “Range”selected):
3.00
Max Credit Hours:
3.00
Select if Repeatable:
Off
Maximum Repeatable Credits:
(N/A)
Total Completions Allowed:
(N/A)
Allow Multiple Enrollments in Term:
No
Course Length:
14 weeks (autumn or spring)
Off Campus:
Never
Campus Location:
Columbus
Instruction Modes:
In Person (75-100% campus; 0-24% online)
Prerequisites and Co-requisites:
Prereq: Grad standing in Engineering, or permission of instructor.
Electronically Enforced:
No
Exclusions:
(N/A)
Course Goals / Objectives:
Be able to identify and explain instances of cellular plasticity associated with pathophysiological processes
Be able to identify and explain therapeutic approaches based on controlling cell and tissue plasticity
Be able to explain how engineering approaches can be applied towards developing cell and tissue reprogramming methodologies.
Students will be able to identify and explain what are some of the barriers to cell and tissue reprogramming
Check if concurrence sought:
No
Contact Hours:
| Topic | LEC | REC out-of-class | REC in-class | Weekly LAB out-of-class | Weekly LAB in-class |
|---|---|---|---|---|---|
| Cell and tissue plasticity within the context of disease | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Methods to control cell and tissue plasticity | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Reprogramming models: direct vs. indirect reprogramming | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Underlying mechanisms of cellular reprogramming | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Barriers to cellular reprogramming | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Cell and gene therapies | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Leveraging cellular reprogramming for therapeutic applications | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Total | 42 | 0 | 0 | 0 | 0 |
Grading Plan:
Letter Grade
Course Components:
Lecture
Grade Roster Component:
Lecture
Credit by Exam (EM):
No
Grades Breakdown:
| Aspect | Percent |
|---|---|
| Attendance | 10% |
| Participation | 10% |
| Quizzes | 20% |
| Homeworks | 20% |
| Paper | 20% |
| Final project | 20% |
Representative Textbooks and Other Course Materials:
| Title | Author | Year |
|---|---|---|
| Cellular Dedifferentiation and Regenerative Medicine | Xiaobing Fu, Andong Zhao, Tian Hu | |
| Epigenetic Mechanisms in Cellular Reprogramming | Alexander Meissner, Jorn Walter |
ABET-CAC Criterion 3 Outcomes:
(N/A)
ABET-ETAC Criterion 3 Outcomes:
(N/A)
ABET-EAC Criterion 3 Outcomes:
(N/A)
Embedded Literacies Info: