BIOMEDE 6430
Transcript Abbreviation:
Mechbio MSK System
Course Description:
Provides a general overview of mechanobiology in development and disease followed by a more in-depth assessment of the specific mechanical signals and pathways that are involved in shaping development of the intervertebral disc, cartilage, and bone.
Course Levels:
Graduate (5000-8000 level)
Designation:
Required
General Education Course:
(N/A)
Cross-Listings:
(N/A)
Credit Hours (Minimum if “Range”selected):
3.00
Max Credit Hours:
3.00
Select if Repeatable:
Off
Maximum Repeatable Credits:
(N/A)
Total Completions Allowed:
(N/A)
Allow Multiple Enrollments in Term:
No
Course Length:
14 weeks (autumn or spring)
Off Campus:
Never
Campus Location:
Columbus
Instruction Modes:
In Person (75-100% campus; 0-24% online)
Prerequisites and Co-requisites:
Prereq: Grad standing in Engineering, or permission of instructor.
Electronically Enforced:
No
Exclusions:
(N/A)
Course Goals / Objectives:
The students will describe the multiple mechanisms (extrinsic and intrinsic) involved in translation of biomechanical signals to biological signals in musculoskeletal development and disease.
The students will evaluate and critique ethical considerations in MSK research
The students will enhance their communication skills through presentation of current and new scientific ideas
The students will write a grant proposal that translates the concepts they learned from development and disease to tissue engineering strategies and identify targeted therapeutics based on engineering solutions
Check if concurrence sought:
No
Contact Hours:
| Topic | LEC | REC out-of-class | REC in-class | Weekly LAB out-of-class | Weekly LAB in-class |
|---|---|---|---|---|---|
| Overview of the Musculoskeletal system | 3.0 | 0.0 | 0 | 0.0 | 0 |
| Development of Musculoskeletal system | 3.0 | 0.0 | 0 | 0.0 | 0 |
| Mechanobiology/Mechanotransduction | 3.0 | 0.0 | 0 | 0.0 | 0 |
| Developmental Mechanobiology/Mechanotransduction | 3.0 | 0.0 | 0 | 0.0 | 0 |
| Developmental concepts to tissue engineer tissues | 7.5 | 0.0 | 0 | 0.0 | 0 |
| Developmental Mechanobiology of the Intervertebral Disc, Cartilage and Bone | 7.5 | 0.0 | 0 | 0.0 | 0 |
| Disease and Mechanobiology/Mechanotransduction | 5.0 | 0.0 | 0 | 0.0 | 0 |
| Model systems for studying Mechanobiology/Mechanotransduction | 5.0 | 0.0 | 0 | 0.0 | 0 |
| Changes in Mechanobiology/ Mechanotransduction with Disease – Intervertebral disc, Cartilage and Bone | 5.0 | 0.0 | 0 | 0.0 | 0 |
| Total | 42 | 0 | 0 | 0 | 0 |
Grading Plan:
Letter Grade
Course Components:
Lecture
Grade Roster Component:
Lecture
Credit by Exam (EM):
No
Grades Breakdown:
| Aspect | Percent |
|---|---|
| Participation | 10% |
| Take home quizzes | 40% |
| Ethics case study | 10% |
| Presentation | 10% |
| Grant proposal | 30% |
Representative Textbooks and Other Course Materials:
| Title | Author | Year |
|---|---|---|
| Biology | Peter Raven, et al. | |
| The Skeletal System | Olivier Pourquie | |
| Skeletal Function and Form - Mechanobiology of Skeletal Development, Aging, and Regeneration | Dennis Carter and Gary S. Beaupre |
ABET-CAC Criterion 3 Outcomes:
(N/A)
ABET-ETAC Criterion 3 Outcomes:
(N/A)
ABET-EAC Criterion 3 Outcomes:
(N/A)
Embedded Literacies Info: