BIOMEDE 6170
Transcript Abbreviation:
Micr Biomech
Course Description:
Physical principles and modes of light microscopy and atomic force microscopy and their applications for probing biomechanical properties.
Course Levels:
Graduate (5000-8000 level)
Designation:
Elective
General Education Course:
(N/A)
Cross-Listings:
MECHENG 6711
Credit Hours (Minimum if “Range”selected):
3.00
Max Credit Hours:
(N/A)
Select if Repeatable:
Off
Maximum Repeatable Credits:
(N/A)
Total Completions Allowed:
(N/A)
Allow Multiple Enrollments in Term:
No
Course Length:
14 weeks (autumn or spring)
Off Campus:
Never
Campus Location:
Columbus
Instruction Modes:
In Person (75-100% campus; 0-24% online)
Prerequisites and Co-requisites:
Pre-Req: Grad Standing in Engineering
Electronically Enforced:
Yes
Exclusions:
MECHENG 6711
Course Goals / Objectives:
Describe the physical principles involved in light and atomic force microscopy image formation.
-Derive Gauss's lensmaker equation and use it to ascertain chromatic aberration.
-Determine spring constant of a AFM cantilever from its geometry
-Derive Gauss's lensmaker equation and use it to ascertain chromatic aberration.
-Determine spring constant of a AFM cantilever from its geometry
Label components and carry out alignment procedures for microscopes.
-Perform Koehler alignment on inverted and upright light microscopes.
-Mount and align an AFM cantilever in a Multimode AFM
-Perform Koehler alignment on inverted and upright light microscopes.
-Mount and align an AFM cantilever in a Multimode AFM
Propose methods for nano and micro-scale biomechanical testing.
-Describe experimental approaches to measure persistence length of single molecules and fibers
-Analyze AFM-nanoindentation curves via Hertz or Oliver-Pharr models
-Describe experimental approaches to measure persistence length of single molecules and fibers
-Analyze AFM-nanoindentation curves via Hertz or Oliver-Pharr models
Check if concurrence sought:
No
Contact Hours:
| Topic | LEC | REC out-of-class | REC in-class | Weekly LAB out-of-class | Weekly LAB in-class |
|---|---|---|---|---|---|
| Transmitted and Reflected Light Microscopy | 12 | 0 | 0 | 0 | 3 |
| Light microscopy in Biomechanics | 8.5 | 0 | 0 | 0 | 0 |
| Atomic Force Microscopy | 9 | 0 | 0 | 0 | 1.5 |
| AFM in Biomechanics | 6 | 0 | 0 | 0 | 0 |
| Total | 35.5 | 0 | 0 | 0 | 4.5 |
Grading Plan:
Letter Grade
Course Components:
Lecture
Grade Roster Component:
Lecture
Credit by Exam (EM):
No
Grades Breakdown:
| Aspect | Percent |
|---|---|
| Lab Reports | 5% |
| Homework Assignments | 25% |
| Journal Presentations | 20% |
| Midterms (2) | 50% |
Representative Textbooks and Other Course Materials:
| Title | Author | Year |
|---|---|---|
| Fundamentals of Light Microscopy and Electronic Imaging | Douglas B. Murphy and Michael W. Davidson | |
| Atomic force microscopy for biologists | V.J. Morris, A.R. Kirby and A.P. Gunning |
ABET-CAC Criterion 3 Outcomes:
(N/A)
ABET-ETAC Criterion 3 Outcomes:
(N/A)
ABET-EAC Criterion 3 Outcomes:
(N/A)
Embedded Literacies Info: