BIOMEDE 5635
Transcript Abbreviation:
Cellular Nanotech
Course Description:
Application of nanotechnology to cells for sensing and subcellular manipulation. Synthesis and biological modification of quantum dots and magnetic nanostructures, their unique material properties, and their application.
Course Levels:
Undergraduate (1000-5000 level)
Graduate (5000-8000 level)
Designation:
Elective
General Education Course:
(N/A)
Cross-Listings:
Cross-listed in CBE 5735.
Credit Hours (Minimum if “Range”selected):
3.00
Max Credit Hours:
3.00
Select if Repeatable:
Off
Maximum Repeatable Credits:
(N/A)
Total Completions Allowed:
(N/A)
Allow Multiple Enrollments in Term:
No
Course Length:
14 weeks (autumn or spring)
12 weeks (summer only)
Off Campus:
Never
Campus Location:
Columbus
Instruction Modes:
In Person (75-100% campus; 0-24% online)
Prerequisites and Co-requisites:
Prereq: Sr or Grad standing in Engineering, or permission of instructor.
Electronically Enforced:
No
Exclusions:
Not open to students with credit for 765 or ChBE 735.
Course Goals / Objectives:
Describe types of inorganic nanostructures used in biology, their properties, synthesis, and surface modification
Describe mechanisms of nanostructure toxicity
Explain why inorganic nanoparticles are excellent imaging agents and give examples of their use in this application
Explain how nanoparticles can be used to alter cell adhesion and migration
Describe the difficulties inherent in delivering nanostructures to the cytoplasm
Describe how nanostructures can interface with cellular transport systems
Describe and give examples of nanostructures used to manipulate free and bound cellular proteins
Explain how nanostructures can be used for cellular delivery; give examples of delivery for cancer treatment and gene therapy
Check if concurrence sought:
No
Contact Hours:
| Topic | LEC | REC out-of-class | REC in-class | Weekly LAB out-of-class | Weekly LAB in-class |
|---|---|---|---|---|---|
| Introduction to Nanostructures | 2.0 | 0.0 | 0 | 0.0 | 0 |
| Synthesis of Nanostructures | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructure Toxicity and Modifications for Biological Use | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructures for Sensing | 6.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructures to Modify Cell Adhesion and Migration | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructure Cellular Entry | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Intracellular Transport of Nanostructures | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructures for Controlled Delivery | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructures for Cancer Treatment | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Nanostructure to Manipulate Proteins | 4.0 | 0.0 | 0 | 0.0 | 0 |
| Total | 40 | 0 | 0 | 0 | 0 |
Grading Plan:
Letter Grade
Course Components:
Lecture
Grade Roster Component:
Lecture
Credit by Exam (EM):
No
Grades Breakdown:
| Aspect | Percent |
|---|---|
| Homework | 30% |
| Quizzes | 20% |
| Group Project | 15% |
| Midterm Exam | 15% |
| Final Exam | 20% |
Representative Textbooks and Other Course Materials:
| Title | Author | Year |
|---|---|---|
| Introduction to Nanotechnology, Wiley (2003) | Charles P. Poole, Jr., Frank J. Owens | |
| Molecular Biology of the Cell, 4th Edition, Garland Publishing (2002)* | Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, James D. Watson |
ABET-CAC Criterion 3 Outcomes:
(N/A)
ABET-ETAC Criterion 3 Outcomes:
(N/A)
ABET-EAC Criterion 3 Outcomes:
(N/A)
Embedded Literacies Info: